MySkin® is the autologous preparation of keratinocytes from patients for use on burns. This is a wound-healing product that uses viable cultured skin cells and delivered as a spray. MySkin® can be applied directly to the patient’s burns to promote re-epithelialisation. The MySkin® spray can also be used for chronic wounds or ulcers.
MySkin® is available as part of a specialist care package for burns patients and is made available as an unlicensed medicine under the Medicines and Healthcare Products Regulatory Authority (MHRA) ‘Specials’ route.
Patient keratinocytes are propagated from a skin biopsy grown in media free from animal products. The turnaround of cells, from biopsy to wound application, is approximately 2 -3 weeks.
The MySkin® spray contains 2ml of keratinocytes in suspension which can cover an area of approximately 100cm2. There can be significant variation in cell numbers available which can be attributed to a number of factors e.g. biopsy thickness, patient age, co-morbidities, contamination etc. The cultures are maintained in aseptic conditions in our cGMP cleanrooms.
Below are some references on earlier publications on MySkin and the use of harvested keratinocytes for wound healing.
Simplifying the delivery of melanocytes and keratinocytes for the treatment of vitiligo using a chemically defined carrier dressing – Authors: Eves PC, Bullett NA, Haddow D, et al.; Source: JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 128; Issue: 6; Pages: 1554-1564; Published: JUN 2008
Randomized, controlled, single-blind study on use of autologous keratinocytes on a transfer dressing to treat non-healing diabetic ulcers – Authors: Moustafa M, Bullock AJ, Creagh TM, et al.; Source: REGENERATIVE MEDICINE; Volume: 2; Issue: 6; Pages: 887-902; Published: NOV 2007
Clinical experience using cultured epithelial autografts leads to an alternative methodology for transferring skin cells from the laboratory to the patient – Author(s): Hernon CA, Dawson RA, Freedlander E, et al.; Source: REGENERATIVE MEDICINE; Volume: 1; Issue: 6; Pages: 809-821; Published: NOV 2006